Doctor's Search

Next steps: Trial Selection & Development

September 6, 2019

Which trials have we selected to move forward with?

  • Wound irrigation to prevent SSIs
  • Coffee to reduce post-operative ileus
  • Regional nerve blocks (+/- ice packs) to reduce postoperative pain and narcotic use
  • Abscess packing (vs. no packing) for wound healing, pain and fistula formation.

What are the next steps?

We are in the process of establishing steering committees (composed of a content expert, a methodological expert, a resident lead, a patient lead, etc.) and selecting the potential sites for pilot trials to demonstrate the feasibility of this novel approach. We have also begun developing the trial protocols and the research infrastructure to conduct pragmatic clinical trials (i.e., an umbrella research ethics board protocol, creation of data linkages between existing data collection mechanisms, and web-based randomization and integrated consent). We are continuing to search for other potential trial questions and to systematically review the evidence surrounding them.

How can you get involved?

If you would like to get involved with the IMPACTS program in any capacity, please contact paul.karanicolas@sunnybrook.ca and we would be happy to explore possibilities with you!